The discovery of diet pills that made spending hours in a fitness center and also following a rigorous dieting program redundant to a certain extent, produced a rage in the market. They turned out to be a blessing in disguise for the entire pharmaceutical industry, which is modern earning of massive revenues with the sale of these pills. It has been estimated that more than 20 million of Americans consume diet pills each year.
The History of Diet Pills
It had been during the ten years of 1950s when science and medicine had been producing striking achievements that these products had been initially given by the doctors for the individuals. The doctors recommended amphetamines, a drug applied to the World War II to keep soldiers alert and active, for fat reduction objective. One of the side effects of amphetamines was appetite suppression which led doctors in prescribing them as weight loss supplements. Before long numerous weight loss individuals underwent amphetamines led substance abuse problems as well as its prescription was inhibited.
It had been in 1970s when health consciousness sprung up to its pinnacle as well as fitness became a world wide craze. Weight reduction became the title of the game and the pharmaceutical industry saw an unexpected boom in the demand for them. The first such drugs in this era were basically amphetamines derivatives, normally referred to as «speed». Afterwards, exipure customer reviews (click the following internet site) a variety of fat loss pills flooded the market.
Food as well as Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, that was followed by dexfenfluramine (Redux) in 1996. Then came the diet drug Phentermine, a sympathomimetic appetite suppressant, which was authorized by the FDA in 1997. Many doctors prescribed Phentermine in conjunction with fenfluramine. The combined prescription of both the prescription drugs was aptly named fen phen.
The era of fen phen quickly declined with accounts of heart valve disease resulting from the combined use of both prescriptions began to surface. The makers withdrew fenfluramine and dexfenfluramine from the industry, therefore ending the principle of fen-phen.
The most popular weight reduction medicines which are prescribed in the US are sympathomimetic appetite suppressants such as Phentermine. These drugs greatly influence the neurotransmitters in such a manner that leads to a loss in appetite.
Other weight loss supplements that received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 and 2001 respectively. While Orlistat is a lipase inhibitor which inhibits the absorption of dietary fats into the body, Sinutramine acts on brain through serotonin, norepinephrine and dopamine reuptake inhibition.